Substituted pyrazinones, pyridines and pyrimidines as...

Details Substituted pyrazinones, pyridines and pyrimidines as... Substituted pyrazinones, pyridines and pyrimidines as...

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61K 31/506 (2006.01) A61K 31/519 (2006.01) A61K 31/52 (2006.01) A61K 31/522 (2006.01) A61K 31/538 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2446980

Compounds provided herein are novel substituted pyrazinones, pyridines and pyrimidines of Formula (I) and (II):[Insert Formula (1) and Formula (II)]Such compounds are particularly useful as CRF receptor ligands, and hence, in the treatment of various neurologically-related disorders such as affective disorder, anxiety and depression.

Cette invention concerne des pyrazinones, pyridines et pyrimidines représentés par les formules (I) et (II). Ces composés sont particulièrement utiles en tant que ligands récepteurs de la corticolibérine et conviennent bien par la même pour le traitement de divers troubles d'ordre neurologique tels que les troubles affectifs, l'anxiété et la dépression.

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