Substituted pyrazoles as p38 kinase inhibitors

Details Substituted pyrazoles as p38 kinase inhibitors Substituted pyrazoles as p38 kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 453/02 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2291115

A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula (I) wherein R1, R2, R3 and R4 are as described in the specification.

L'invention concerne une classe de dérivés de pyrazoles, utile pour traiter des troubles associés à la p38 kinase. Des composés particulièrement intéressants sont définis par la formule (I), dans laquelle R?1¿, R?2¿, R?3¿ et R?4¿ sont tels que décrits dans la description.

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