Substituted pyrazoles as p38 kinase inhibitors

Details Substituted pyrazoles as p38 kinase inhibitors Substituted pyrazoles as p38 kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) A61K 31/52 (2006.01) A61P 29/00 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 231/00 (2006.01) C07D 293/00 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2351725

A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula (IA), wherein R1, R2, R3 and R4 are as described in the specification.

L'invention décrit une classe de dérivés de pyrazole utilisés dans le traitement de troubles induits par la kinase p38. Les composés revêtant un intérêt particulier sont définis par la formule (IA) dans laquelle R?1¿, R?2¿, R?3¿ et R?4¿ sont tels que définis dans la description.

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