Substituted pyrazoles, compositions containing such...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/04 (2006.01) A61K 31/395 (2006.01) A61K 31/4709 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) C07D 401/10 (2006.01) C07D 403/04 (2006.01) C07D 403/10 (2006.01) C07D 405/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2574147

The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.

La présente invention concerne des pyrazoles substitués, des compositions contenant de tels composés et des méthodes de traitement. Ces composés constituent des antagonistes du récepteur de glucagon et sont, donc, utilisés dans le traitement, la prévention ou l'ajournement de l'apparition de diabète sucré de type 2.

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