Substituted pyridazinones as inhibitors of p38

Details Substituted pyridazinones as inhibitors of p38 Substituted pyridazinones as inhibitors of p38

C - Chemistry, Metallurgy

07

D

C07D 237/14 (2006.01) A61K 31/501 (2006.01) C07D 237/16 (2006.01) C07D 237/18 (2006.01) C07D 237/22 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 405/12 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2474239

(Formula I); Disclosed are substituted pyridazinones that are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical composition containing the pyridazinone compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.

L'invention concerne des pyridazinones substituées utiles pour le traitement des maladies et des affections qui sont engendrées ou exacerbées par une activité de MAP kinase p38 et/ou de TNF non régulée. L'invention concerne également une composition pharmaceutique renfermant les composés considérés, des procédés relatifs à l'élaboration de ces composés, et des procédés thérapeutiques reposant sur l'utilisation des composés en question.

Affiliated with

Also associated with

Rating

Substituted pyridazinones as inhibitors of p38 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted pyridazinones as inhibitors of p38, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted pyridazinones as inhibitors of p38 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1594229