Substituted pyrimidine compounds and their use

Details Substituted pyrimidine compounds and their use Substituted pyrimidine compounds and their use

C - Chemistry, Metallurgy

07

D

C07D 239/56 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) C07D 239/38 (2006.01) C07D 239/46 (2006.01) C07D 239/60 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2195241

The use is disclosed of pyrimidine compounds having the formula (I), in which R1, R2, R3, A, B and Ar have the meanings given in the description. These compounds have a high affinity for the dopamine D3 receptor and are therefore useful for treating diseases that respond to dopamine D3 ligands.

L'invention concerne l'utilisation de composés de pyrimidine ayant la formule (I), dans laquelle R?1¿, R?2¿, R?3¿, A, B et Ar ont la notation donnée dans la description. Ces composés ont une affinité élevée pour le récepteur de la dopamine D¿3? et sont par conséquent utiles pour traiter des maladies réagissant aux ligands de la dopamine D¿3?.

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