C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/505 (2006.01) C07D 239/42 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C12Q 1/32 (2006.01)
Patent
CA 2048842
Substituted pyrimidine derivatives, a process for the preparation thereof and the use thereof as reagents Pyrimidine derivatives of the formula I Image in which R1, R2, X and Y have the stated meaning, the salts thereof and a process for the preparation thereof are described. Because of their sorbitol-accumulating activity, they are suitable fox use as reagents for an advantageous pharmacological screening model for testing aldose reductase inhibitors.
Geisen Karl
Lang Hans-Jochen
Nimmesgern Hildegard
Utz Roland
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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