Substituted pyrimidine derivatives, their uses and a process...

Details Substituted pyrimidine derivatives, their uses and a process... Substituted pyrimidine derivatives, their uses and a process...

C - Chemistry, Metallurgy

07

D

167/211, 260/246

C07D 401/14 (2006.01) A61K 31/505 (2006.01) C07D 239/42 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2010588

Pyrimidine derivatives of the formula I Image in which R1, R2, R3, R4 and R5 have the indicated meanings, the salts thereof, and a process for the preparation thereof are described. Because of their sorbitol-accumulating activity, they are suitable as a tool in a pharmacological screening model for aldose reductase inhibitors.

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