Substituted pyrimidoindoles

Details Substituted pyrimidoindoles Substituted pyrimidoindoles

C - Chemistry, Metallurgy

07

D

260/242.01

C07D 471/20 (2006.01) C07D 487/04 (2006.01) C07D 487/20 (2006.01)

Patent

CA 1281322

H-372-f ABSTRACT SUBSTITUTED PYRIMIDOINDOLES Pyrimidoindoles of formula (I) Image (I) and their pharmaceutically acceptable acid addition salts, wherein R represents lower alkyl a mono- or bi- cyclic aryl radical or a group of formula R3O-B-[where R3O is (lower)alkoxy,aryl(lower)alkoxy or hydroxy and B is a lower alkylene chain optionally containing one double or triple bond], R1 and R2 which may be the same or different each represent hydrogen, hydroxyl, lower alkyl, lower alkoxy, halo(lower)alkyl, halogen, amino or mono- or di(lower) alkylamino and A, together with the carbon atom to which it is attached, represents 5, 6 or 7 membered saturated carbocyclic or heterocyclic ring,are useful as hypoglycaemics.

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