Substituted pyrr0lidin-2-0nes , piperidin-2-0nes and...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 207/27 (2006.01) A61K 31/4015 (2006.01) A61K 31/4412 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) C07D 211/76 (2006.01) C07D 275/02 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 409/06 (2006.01)

Patent

CA 2610326

The invention relates to compounds of the formula (I), in which A, R1 , R2, R3, R4, R5, R6, R7 and n have the meanings stated in the claims. The compounds are particularly suitable as antiarrhythmic active ingredients, in particular for the treatment and prophylaxis of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.

La présente invention concerne des composés de formule (I), dans laquelle R1, R2, R3, R4, R5, R6, R7 et n ont les significations énoncées dans les revendications. Les composés sont particulièrement appropriés comme ingrédients actifs antiarythmiques, en particulier pour le traitement et la prophylaxie d~arythmies auriculaires, par exemple, une fibrillation auriculaire (FA) ou un flutter auriculaire.

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