C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/14 (2006.01) A61K 31/4015 (2006.01) A61K 31/404 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2385071
Disclosed are novel substituted pyrroles having formula (I). These compounds and their pharmaceutically acceptable salts are suitable for administration to patients as continuous infusion solution and are useful in the treatment and/or control of cell proliferative disorders, in particular cancer. Also disclosed are pharmaceutical compositions containing the foregoing compounds and their use for the treatment and/or control of cancer.
L'invention concerne de nouveaux pyrroles substitués représentés par la formule (I). Ces composés et leurs sels pharmaceutiquement acceptables conviennent pour être administrés à des patients sous forme d'une solution d'infusion continue, et sont utiles pour traiter et ou réguler des troubles cellulaires prolifératifs, en particulier le cancer. L'invention concerne également des compositions pharmaceutiques contenant les composés précités, et leur utilisation pour traiter et/ou vaincre le cancer.
Fotouhi Nader
Kong Norman
Liu Emily Aijun
Lovey Allen John
Mullin John Guilfoyle Jr.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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