Substituted pyrrolidine and piperidine compounds,...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 207/10 (2006.01) A61K 31/164 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) A61P 29/00 (2006.01) C07C 233/08 (2006.01) C07D 209/04 (2006.01) C07D 211/36 (2006.01) C07D 265/02 (2006.01) C07D 277/04 (2006.01)

Patent

CA 2718959

The present application relates to pyrrolidine, piperidine, and other nitrogen- containing heterocyclic derivatives and the use of these compounds for treating and preventing pam or inflammation. The analgesic compounds demonstrate efficacy in the treatment of neuropathic pain resulting from a variety of conditions such as diabetic neuropathy, HN infections, and postherpetic neuralgia.

La présente invention porte sur des dérivés de pyrrolidine, de pipéridine et d'autres dérivés hétérocycliques contenant de l'azote et sur l'utilisation de ces composés pour le traitement et la prévention de la douleur ou d'une inflammation. Les composés analgésiques présentent une efficacité dans le traitement d'une douleur neuropathique résultant de diverses affections telles que la neuropathie diabétique, les infections à VIH et la névralgie post-herpétique.

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