C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/325.2, 260/3
C07D 207/02 (2006.01) C07D 207/327 (2006.01) C07D 213/65 (2006.01) C07D 295/033 (2006.01) C07D 403/02 (2006.01)
Patent
CA 1152996
Abstract of the disclosure: Substituted pyrrolidinylsulfamoylbenzoic acid derivatives of the formula Image in which R1 and R2 denote C1-C4alkyl and one of the radicals R1 or R2 may be hydrogen, R3 and R3 denote hydrogen or C1-C4alkyl or together denote a C-C linkage, R4 and R4' denote hydrogen, halo- gen, CF3, alkyl or C1-C2alkoxy, hydroxy, amino or dimethylamino in the various positions of the aryl nucleus, or together denote 3,4-methylenedioxy, R5 and R6 denote hydrogen, C1-C4alkyl or benzyl, Ar denotes phenyl or a 5-membered or 6-membered hetero- aromatic ring containing a O, S or N atom and X is omitted or denotes oxygen, sulfur, NH, or CH2 and their pharmaceutically acceptable salts with bases or acids have a salidiuretic action and can be used for the treatment of oedomatous diseases.
351130
Bormann Dieter
Merkel Wulf
Muschaweck Roman
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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