Substituted pyrrolines as kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/14 (2006.01) A61K 31/404 (2006.01) A61K 31/416 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 29/00 (2006.01) A61P 37/02 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2488798

The present invention is directed to novel substituted pyrroline compounds of formula (I) useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual- kinase mediated disorder.

L'invention concerne des composés de pyrroline substitués utiles comme inhibiteurs de kinase ou de kinase-2, des procédés relatifs à l'élaboration de ces composés, et des procédés relatifs au traitement ou à l'atténuation de troubles dont la médiation est assurée par la kinase ou la kinase-2.

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