Substituted quinazoline or pyridopyrimidine derivative

Details Substituted quinazoline or pyridopyrimidine derivative Substituted quinazoline or pyridopyrimidine derivative

C - Chemistry, Metallurgy

07

D

C07D 513/04 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2560286

A compound having the activity of glucokinase activation and being useful for the prevention or treatment of diabetes, etc., represented by the formula: (I) [wherein X is a nitrogen atom, etc.; Y is an oxygen atom, etc.; R1 is an optionally substituted 5 to 6-membered heteroaryl group, etc.; R2 is a hydrogen atom or a fluorine atom; and the ring A is an optionally substituted monocyclic or bicyclic heteroaryl group of the formula: (II) ], or a pharmacologically acceptable salt thereof.

Un composé ayant une activité d'activation de la glucokinase et étant utile pour la prévention ou le traitement du diabète, etc., représenté par la formule : (I) [où X est un atome d~azote, etc. ; Y est un atome d~oxygène, etc.; R?1¿ est un groupe hétéroaryle de 5 à 6 éléments facultativement substitué, etc. ; R?2¿ est un atome d~hydrogène ou un atome de fluor ; et le cycle A est un groupe hétéroaryle monocyclique ou bicyclique facultativement substitué de formule : (II)], ou un sel acceptable du point de vue pharmacologique de celui-ci.

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