Substituted quinoline compounds

Details Substituted quinoline compounds Substituted quinoline compounds

C - Chemistry, Metallurgy

07

D

C07D 215/48 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61P 3/04 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2555133

This invention relates to MTP/Apo-B secretion inhibitors of Formula (I) wherein R1-R7, X1, m and n are as defined in the specification, as well as pharmaceutical compositions comprising the compounds, and methods of use of the compounds and compositions. The compounds of the invention are useful in treating obesity and associated diseases, conditions or disorders.

L'invention concerne des inhibiteurs de sécrétion de MTP/Apo-B de formule (I) dans laquelle R?1¿-R?7¿, X?1¿, m et n ont la signification indiquée dans la description, ainsi que des compositions pharmaceutiques comprenant ces composés, et des méthodes d'utilisation desdits composés et compositions. Les composés de l'invention sont utiles dans le traitement de l'obésité et de maladies, d'états et de troubles associés.

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