C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/271
C07D 471/04 (2006.01) C07D 455/02 (2006.01)
Patent
CA 1100970
ABSTRACT OF THE DISCLOSURE The present invention relates to substituted quinolizidine and indolizidine derivatives having anticholinergic, anti- histamic, antitussive and analgetic activities and to a process for producing the same. It has been found that the substituted quinolizidine and indolizidine derivatives having the following formula Image wherein A represents a phenyl group or a 2-thienyl group and n is an integer of 3 or 4 and pharmaceutically accepted acid addition salts thereof as well as quarternary salts thereof, exhibit strong anticholinergic activity but have extremely low side effects.
302858
Ishizuka Miyoko
Kato Hideo
Koshinaka Eiichi
Kurata Sakae
Ogawa Nobuo
Hokuriku Pharmaceutical Co. Ltd.
Johnson Douglas S. Q.c.
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