Substituted quinolylmethoxy anilines

Details Substituted quinolylmethoxy anilines Substituted quinolylmethoxy anilines

C - Chemistry, Metallurgy

07

D

167/226, 260/277

C07D 215/02 (2006.01) A61K 31/47 (2006.01) C07D 215/14 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01)

Patent

CA 1336602

Hither unknown compounds of the Formula (I): Image ( I) are provided herein. In such Formula (I) R1 stands for hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C1-C8-alkyl, or aryl or ar-C1- C4-alkyl, wherein aryl or ar are unsubstituted or substi- tuted phenyl, the above substitution being one or more of the following substituents: halogen, pseudo halogen, tri- fluoro methyl, cyano, nitro, amino, carboxy, carbalkoxy, carbamyl, hydroxy, alkyl or alkoxy; R2, R3, R4, R5, R6, and R7 are the same or different and stand for hydrogen, halogen, pseudo halogen, cyano, nitro, amino, carboxy, carbalkoxy, carbamyl, hydroxy, C1-C8-alkyl, or C1-C6-alkoxy; n and m are the same or different and stand for an integer from 0-6; provided that n cannot be zero when A stands for carboxy and X and Q both stand for a bond; X stands for a bond or for O, S, S(O), S(O)2 or NR8, where R8 is defined as R1 above; Q stands for a bond or for straight or branched, C1- C6-alkylene; A stands for an acidic group, selected from the group consisting of carboxy, 1H-tetrazolyl, a sulphonic acid group, a sulfamyl group, a sulphinic acid group and a hydroxamic acid group, or pharmaceutically-acceptable, non- toxic salts or in vivo hydrolyzable esters thereof. Such compounds are of value in human and veterinary practice as lipoxygenase inhibitors and/or leukotriene antagonists.

584360

Affiliated with

Also associated with

Rating

Substituted quinolylmethoxy anilines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted quinolylmethoxy anilines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted quinolylmethoxy anilines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1299125