Substituted sulphonamido phenoxybenzamides

Details Substituted sulphonamido phenoxybenzamides Substituted sulphonamido phenoxybenzamides

C - Chemistry, Metallurgy

07

C

C07C 311/08 (2006.01) A61K 31/18 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2742945

The present invention relates to substituted sulphonamido phenoxybenzamide compounds of general formula (I) in which A, R1, R2, R3, R4, R5, R6, R7, R8 and n are as defined in the claims, to pharmaceutical compositions and combinations containaining said compounds, to methods of preparing said compounds, and to the use of said compounds or compositions for treating hyper- proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.

La présente invention concerne des composés de sulfonamido phénoxybenzamide substitués représentés par la formule générale (I), dans laquelle A, R1, R2, R3, R4, R5, R6, R7, R8 et n sont tels que définis dans les revendications, des compositions pharmaceutiques et des combinaisons contenant lesdits composés, des méthodes de préparation desdits composés, ainsi que l'utilisation desdits composés pour le traitement de troubles hyperprolifératifs et/ou de l'angiogenèse, en tant qu'agent seul ou en combinaison avec d'autres ingrédients actifs.

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