Substituted tetra- and pentapeptide inhibitors of...

Details Substituted tetra- and pentapeptide inhibitors of... Substituted tetra- and pentapeptide inhibitors of...

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 1/02 (2006.01) C07K 1/04 (2006.01) C07K 5/117 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2204144

Inhibitors of protein:farnesyl transferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.

Cette invention se rapporte à des inhibiteurs de l'enzyme protéine:farnésyle transférase, ainsi qu'à des procédés pour leur préparation et des compositions pharmaceutiques les contenant, qui sont utiles pour lutter contre les maladies prolifératives des tissus, telles que le cancer et la resténose.

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