Substituted tetra- and pentapeptide inhibitors of...

Details Substituted tetra- and pentapeptide inhibitors of... Substituted tetra- and pentapeptide inhibitors of...

C - Chemistry, Metallurgy

07

K

C07K 5/117 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 5/103 (2006.01) C07K 7/06 (2006.01) C07K 14/82 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2173590

Inhibitors of protein: farnesyl transferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.

L'invention porte sur des inhibiteurs de la farnésyl-transférase protéinique et sur le procédé de préparation desdits inhibiteurs et de leurs compositions pharmaceutiques, qui s'avèrent utiles dans le contrôle des maladies à prolifération tissulaire y compris le cancer et la sténose récidivante.

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