Substituted tetracycline compounds

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 237/26 (2006.01) A61K 31/65 (2006.01) A61P 25/28 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 33/06 (2006.01) C07D 295/155 (2006.01) C07D 307/54 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2585248

The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.

L'invention concerne, au moins en partie, des composés de tétracycline substitués, pouvant être utilisés pour le traitement de nombreux états réagissant à un composé de ce type, du type infections bactériennes et néoplasmes, et pour d'autres applications connues relativement à de tels composés, comme le blocage de l'efflux de tétracycline et la modulation de l'expression génique.

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