Substituted tetracycline compounds

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 237/26 (2006.01) C07C 43/00 (2006.01) C07C 49/00 (2006.01) C07C 239/18 (2006.01) C07C 251/08 (2006.01) C07C 251/48 (2006.01) C07C 255/25 (2006.01) C07C 255/43 (2006.01) C07C 255/58 (2006.01) C07C 255/59 (2006.01) C07C 271/28 (2006.01) C07C 271/44 (2006.01) C07C 275/34 (2006.01) C07C 279/18 (2006.01) C07C 281/14 (2006.01) C07C 309/61 (2006.01) C07C 311/19 (2006.01) C07C 311/21 (2006.01) C07C 317/48 (2006.01) C07C 323/32 (2006.01) C07C 323/60 (2006.01) C07D 207/16 (2006.01) C07D 211/58 (2006.01) C07D 213

Patent

CA 2479877

The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

L'invention concerne, du moins en partie, de nouveaux composés de tétracycline substituée. Ces composés de tétracycline peuvent être utilisés pour traiter de nombreux états sensibles aux composés de tétracycline, tels que des infections bactériennes et des néoplasmes, ainsi que dans d'autres applications connues de composés de minocycline et de tétracycline en général, telles que le blocage de l'écoulement de tétracycline et la modulation de l'expression génique.

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