Substituted thienoimidazoles, method for production and use...

Details Substituted thienoimidazoles, method for production and use... Substituted thienoimidazoles, method for production and use...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4188 (2006.01) A61P 1/00 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2537695

The invention relates to substituted thienoimidazoles of formula (I) or (II), where R1 to R4 have the meanings given in the claims. Medicaments comprising compounds of this type are useful for the prevention or treatment of diverse diseases. The compounds find application, amongst other things, for the treatment of breathing disorders and snoring, to improve the breathing process, for treatment of chronic and acute diseases of the kidney and the intestine, diseases caused by ischaemic and/or reperfusion events, proliferative or fibrotic diseases, for the treatment or prophylaxis of diseases of the central nervous system, lipometabolism, diabetes, blood clotting and parasitic attack.

L'invention concerne des thiénoimidazoles substitués de formule (I) ou (II), dans lesquelles R1 à R4 ont les significations indiquées dans les revendications. Cette invention concerne également des médicaments contenant des composés de ce type et utiles dans la prévention ou le traitement de diverses maladies. Ainsi, ces composés peuvent être utilisés, entre autres, dans le traitement de troubles respiratoires et de la rhonchopathie ainsi que pour améliorer la commande respiratoire, dans le traitement de maladies rénales et intestinales aiguës et chroniques ainsi que de maladies déclenchées par des événements ischémiques et/ou de reperfusion et des événements proliférants ou fibrosants, dans le traitement ou la prophylaxie de maladies du système nerveux central, du métabolisme lipidique et du diabète, de la coagulation sanguine et de l'infestation parasitaire.

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