Substituted tricyclics

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/02 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/407 (2006.01) A61K 31/435 (2006.01) A61K 31/437 (2006.01) A61K 31/445 (2006.01) C07D 209/82 (2006.01) C07D 209/88 (2006.01) C07D 409/04 (2006.01) C07D 495/16 (2006.01) C07F 9/572 (2006.01)

Patent

CA 2269203

A class of novel tricyclics is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.

La présente invention, qui concerne une classe de composés tricycliques, concerne également l'utilisation de tels composés pour inhiber la libération d'acides gras, laquelle libération résulte d'une médiation sPLA2. Cette inhibition vise à remédier à des états tels qu'un choc septique.

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