Substituted tropyl and pseudotropyl benzoates and their use...

Details Substituted tropyl and pseudotropyl benzoates and their use... Substituted tropyl and pseudotropyl benzoates and their use...

C - Chemistry, Metallurgy

07

D

260/270.5

C07D 451/12 (2006.01) C07D 451/06 (2006.01)

Patent

CA 1202027

TROPYL AND PSEUDOTROPYL ALKYL-BENZOATES AND THEIR USE IN MIGRAINE TREATMENT ABSTRACT OF THE DISCLOSURE Migraine is treated with a pseudotropyl or tropyl benzoate derivative of the following general Formula I:- Image wherein:- n represents O or an integer from 1 to 4 R1 represents C1-C4 alkoxy or chlorine; R2 represents C1-C4 alkyl, C1-C4 alkoxy or halogen provided that R2 is the same as R1 when n is 2, 3 or 4; or a pharmaceutically acceptable salt thereof. With the exception of tropyl-2-chlorobenzoate and tropyl-2,4-,-2,5-,-2,6-dichlorobenzoates, the derivatives of Formula I are novel compounds.

442556

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