(substituted) ureidoacetohydroxamic acids

Details (substituted) ureidoacetohydroxamic acids (substituted) ureidoacetohydroxamic acids

C - Chemistry, Metallurgy

07

C

260/516.2, 260/5

C07C 275/16 (2006.01)

Patent

CA 1079748

ABSTRACT OF THE DISCLOSURE Ureidocetohydroxamic acids of general formula Image wherein R is isobutyl, hydrogen, methyl, benzyl, 4-aminobutyl or hexyl and R1 is hydrogen or benzyl, and methods for their preparation are described. These compounds are patent inhibitors of the enzyme responsible for the con- version of Angiotensin I to the powerful pressor agent Angiotensin II associated with hypertension.

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