Substrate for the determination of plasminogen activators

Details Substrate for the determination of plasminogen activators Substrate for the determination of plasminogen activators

G - Physics

01

J

150/1, 150/9

G01J 3/00 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) C12Q 1/56 (2006.01) G01J 1/00 (2006.01)

Patent

CA 1086614

A SUBSTRATE FOR THE QUANTITATIVE DETERMINATION OF PLASMINOGEN ACTIVATORS ABSTRACT OF THE DISCLOSURE A substrate for the quantitative determination of enzymes in human and mammel body fluids and tissue extracts, which has the structure R1 - X - Y - Z - NH - R2 wherein X represents a group having the formula - NH - ?H - CO - in which R3 is a straight or branched alkyl radical having 1 to 7 carbon atoms or a cyclohexyl or cyclohexylmethyl radical, Y represents a seryl group or a group having the formula - NH - (CH2)n - CO - in which n is an integer from 1 to 7, Z represents an arginyl or lysly group, R1 represents hydrogen or an acyl or sulfonyl group and R2 represents an aromatic hydrocarbon radical which optionally may carry sub- stituents.

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