Substrate peptides

Details Substrate peptides Substrate peptides

C - Chemistry, Metallurgy

07

K

530/7.06

C07K 7/06 (2006.01)

Patent

CA 1308217

NOVEL SUBSTRATE PEPTIDES Abstract of the Disclosure A peptide substrate useful as a substrate for myristoylating enzymes in yeast and mammalian cells is disclosed having an amino acid sequence selected from the group consisting of the following sequences or a physio- logically acceptable amide or salt derivative thereof: Image or Image , wherein R = Ala, Asn, Gln or Ser; S = Ala, Arg, Gln, Glu, Phe or Ser; T = Ala or Lys; W = Ala or Ser; X = Ala, Tyr, or Lys; Y = Arg or Pro; and Z = Arg, Leu or Lys; with the proviso that when S-T-W-X-Y-Z is Ala-Ala-Ala-Ala-Arg-Arg R is not Asn.

543906

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