C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/54 (2006.01) C11D 3/386 (2006.01)
Patent
CA 2376045
The present invention relates to variants of subtilisin-like proteases having decreased immunogenicity relative to their corresponding wild-type proteases. More particularly, the present invention relates to variants having a modified amino acid sequence of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises a substitution of one or more epitope regions. The invention further relates to mutant genes encoding such variants and cleaning and personal care compositions comprising such variants.
La présente invention concerne des variantes de protéases ressemblant à la subtilisine et présentant une immunogénicité inférieure à celles des protéases correspondantes de type sauvage. L'invention concerne plus particulièrement des variantes comportant une séquence d'acide aminé modifiée remplaçant une séquence d'acide aminé de type sauvage, laquelle séquence modifiée comporte une substitution d'au moins une région de l'épitope. L'invention concerne également, d'une part des gènes mutants codant de telles variantes, et d'autre part des compositions de produits d'hygiène domestique est d'hygiène corporelle comprenant de telles variantes.
Rubingh Donn Nelton
Sikorski Elizabeth Ellen
Gowling Lafleur Henderson Llp
The Procter & Gamble Company
LandOfFree
Subtilisin protease variants having amino acid substitutions... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Subtilisin protease variants having amino acid substitutions..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Subtilisin protease variants having amino acid substitutions... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1905314