Subtype-matched inactivated whole virus vaccines for...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 7/06 (2006.01) A61K 39/21 (2006.01)

Patent

CA 2582426

Inactivated whole HIV of a particular subtype is used to prepare vaccines and pharmaceutical compositions containing the vaccines. The vaccines can be used to treat individuals chronically infected with HIV, by inducing a protective cellular immune response in the individuals against the same HIV subtype used to produce the vaccine.

L'invention concerne un VIH entier inactivé d'un sous-type particulier utilisé pour préparer des vaccins, et des compositions pharmaceutiques contenant ces vaccins. Les vaccins de l'invention peuvent être utilisés pour traiter des individus chroniquement infectés par le VIH, en induisant une réponse immunitaire cellulaire de protection chez ces individus, contre le même sous-type de VIH que celui qui a été utilisé pour produire le vaccin.

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