Subunit papillomavirus vaccine and peptides for use therein

Details Subunit papillomavirus vaccine and peptides for use therein Subunit papillomavirus vaccine and peptides for use therein

C - Chemistry, Metallurgy

07

K

C07K 14/025 (2006.01) A61K 39/12 (2006.01) C07K 7/04 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2097916

The invention relates to a subunit papillomavirus vaccine which is protective against anogenital human papillomavirus (HPV) infection. Peptides are also provided which constitute an antigenic component of the vaccine. The peptide includes the sequence DRAHYNI and structural homologues thereof which concern a single amino acid substitution. The peptide is linked directly or indirectly to one or more amino acid sequences which correspond to a B epitope HPV16 and HPV18. The DRAHYNI sequence corresponds to a T helper epitope sequence.

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