Succinamide inhibitors of interleukin-1.beta. converting enzyme

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/05 (2006.01) C07C 233/47 (2006.01) C07C 255/29 (2006.01) C07C 311/10 (2006.01) C07C 311/13 (2006.01) C07D 209/16 (2006.01) C07D 211/14 (2006.01) C07D 213/40 (2006.01) C07D 215/12 (2006.01) C07D 231/56 (2006.01) C07D 233/54 (2006.01) C07D 235/06 (2006.01) C07D 235/08 (2006.01) C07D 249/18 (2006.01) C07D 257/04 (2006.01) C07D 265/28 (2006.01) C07D 307/33 (2006.01) C07D 311/14 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2327507

The present invention provides compounds of Formula (I), pharmaceutical compositions comprising a compound of Formula (I), and methods of treatment of stroke; inflammatory diseases such as rheumatoid arthritis or inflammatory bowel disease; septic shock; reperfusion injury; Alzheimer's disease; shigellosis; and multiple sclerosis.

Cette invention a trait à des composés correspondant à la formule (I), à des compositions pharmaceutiques comprenant un composé correspondant à la formule (I) ainsi qu'à des méthodes de traitement de l'ictus, de maladies inflammatoires telles que la polyarthrite rhumatoïde ou la maladie intestinale inflammatoire, du choc septique, des lésions de perfusion répétée, de la maladie d'Alzheimer, de la dysenterie bacillaire et de la sclérose en plaques.

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