Succinic acid production in a eukaryotic cell

Details Succinic acid production in a eukaryotic cell Succinic acid production in a eukaryotic cell

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C12N 9/02 (2006.01) C12P 7/46 (2006.01)

Patent

CA 2704654

The present invention relates to a recombinant eukaryotic cell selected from a yeast of a filamentous fungus comprising a nucleotide sequence encoding a NAD(H) -dependent fumarate reductase that catalyses the conversion of fumaric acid to succinic acid. The invention further relates to a process for the production of succinic acid wherein the eukaryotic cell according to the present invention is used.

La présente invention concerne une cellule eucaryote recombinante, choisie parmi une levure ou un champignon filamenteux, comprenant une séquence nucléotidique qui code pour une fumarate réductase NAD(H)-dépendante qui catalyse la conversion d'acide fumarique en acide succinique. L'invention concerne en outre un procédé utilisant la cellule eucaryote de l'invention pour produire de l'acide succinique.

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