A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/26 (2006.01)
Patent
CA 2455939
The present invention is directed to a pharmaceutically acceptable taste masking liquid excipient base for administration of a relatively large amount of unpleasant tasting medicines. More particularly, the enhanced sweetness and taste masking effect are produced by the addition of sucralose to the excipient base with maintenance of a pH from about 2 to about 5. The invention is further directed to medicinal compositions comprising such a liquid excipient base and unpleasant tasting medicines. Still further, the invention is directed to a method for taste masking unpleasant tasting medicines through their incorporation into the claimed liquid excipient bases.
La présente invention concerne une base d'excipient liquide pharmaceutiquement acceptable destinée au masquage du goût, permettant l'administration d'une quantité relativement importante de médicaments ayant un goût désagréable. Plus particulièrement, la sucrosité améliorée et l'effet de masquage du goût sont produits par adjonction de sucralose à une base d'excipient en maintenant un pH compris entre environ 2 et environ 5. Cette invention concerne également des compositions médicinales comprenant une telle base d'excipient liquide et des médicaments ayant un goût désagréable. En outre, l'invention concerne un procédé de masquage du goût pour des médicaments ayant un goût désagréable, consistant à incorporer ces médicaments dans les bases d'excipient liquides décrites dans cette invention.
Dickerson Jay
Jaeger David
Trimmer Annabelle
Robic
Wyeth
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