Sugar chain-capturing substance and use thereof

Details Sugar chain-capturing substance and use thereof Sugar chain-capturing substance and use thereof

C - Chemistry, Metallurgy

07

C

C07C 281/02 (2006.01) C07C 233/18 (2006.01) C08F 20/60 (2006.01) C40B 30/04 (2006.01) C40B 40/12 (2006.01) C40B 50/14 (2006.01) C40B 50/18 (2006.01) G01N 1/28 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2660300

The invention provides a method for preparing a sample characterized by binding substance A containing a hydrazide group to a sugar chain and/or a sugar derivative via hydrazone formation between the hydrazide group of the substance A and the reducing end of the sugar chain and/or sugar derivative thereby to enable the separation and purification of the sugar chain and/or sugar derivative for an analytical sample from a biological sample containing the sugar chain and/or sugar derivative by a simple operation.

L'invention concerne un procédé de préparation d'un échantillon caractérisé en ce qu'il consiste à lier une substance A, contenant un groupe hydrazide, à une chaîne glucidique et/ou un dérivé glucidique par formation d'hydrazone entre le groupe hydrazide de la substance A et l'extrémité réductrice de la chaîne et/ou du dérivé glucidique, afin de permettre la séparation et la purification de ladite chaîne ou dudit dérivé glucidique et ainsi produire de façon simple un échantillon analytique à partir d'un échantillon biologique contenant ledit dérivé ou ladite chaîne.

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