Sugar derivatives of hydromorphone, dihydromorphine and...

C - Chemistry – Metallurgy – 07 – H

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C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 43/00 (2006.01) C07H 17/02 (2006.01)

Patent

CA 2455774

Glucoside and glucuronide derivatives ofhydromorphone, dihydromorphine, and dihydroisomorphine and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising a glucoside or glucuronide derivative ofhydromorphone, dihydromorphine, or dihydroisomorphine or a pharmaceutically acceptable salt thereof; and methods for treating or preventing pain in a patient comprising administering to a patient in need thereof a glucoside or glucuronide derivative ofhydromorphone, dihydromorphine, or dihydroisomorphine or a pharmaceutically acceptable salt thereof are disclosed.

Dérivés glucoside et glucuronide d'hydromorphone, de dihydromorphine et de dihydroïsomorphine ainsi que leurs sels pharmaceutiquement acceptables; compositions pharmaceutiques comprenant un dérivé d'hydromorphone, de dihydromorphine et de dihydroïsomorphine ou un sel pharmaceutiquement acceptable; et procédés de traitement ou de prévention de la douleur chez un patient, qui consistent à administrer au patient un dérivé glucoside et glucuronide d'hydromorphone, de dihydromorphine ou de dihydroisomorphine ou d'un sel pharmaceutiquement acceptable.

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