Sulfamide-metalloprotease inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 295/22 (2006.01) A61K 31/18 (2006.01) A61K 31/435 (2006.01) C07C 307/06 (2006.01) C07D 211/16 (2006.01) C07D 211/22 (2006.01) C07D 211/34 (2006.01) C07D 211/36 (2006.01) C07D 211/44 (2006.01) C07D 211/46 (2006.01) C07D 211/50 (2006.01) C07D 211/54 (2006.01) C07D 211/58 (2006.01) C07D 211/62 (2006.01) C07D 213/74 (2006.01) C07D 239/42 (2006.01) C07D 295/26 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2278694

This invention relates to sulfamides of formula (I) wherein R1, R2, R3, R10, R20, R21 are as defined in the specifications and the claims that are inhibitors of metalloproteases, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.

L'invention concerne des sulfamides présentant la formule (I). Dans cette dernière, R<1>, R<2>, R<3>, R<10>, R<20>, R<21> sont tels que définis dans les spécifications et les revendications, c'est-à-dire, des inhibiteurs de métalloprotéases. L'invention concerne aussi des compositions pharmaceutiques contenant ces produits, des procédés pour leur utilisation et des procédés pour leur préparation.

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