Sulfamide, sulfamate, sulfonamide, urea, amide, alpha,...

Details Sulfamide, sulfamate, sulfonamide, urea, amide, alpha,... Sulfamide, sulfamate, sulfonamide, urea, amide, alpha,...

C - Chemistry, Metallurgy

07

D

C07D 498/18 (2006.01) A61K 31/165 (2006.01) A61K 31/192 (2006.01) A61K 31/4985 (2006.01) A61K 31/4995 (2006.01) A61K 31/504 (2006.01) A61K 31/5365 (2006.01) A61K 38/18 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07C 57/58 (2006.01) C07C 59/64 (2006.01) C07C 59/68 (2006.01) C07C 233/65 (2006.01) C07C 235/46 (2006.01) C07D 471/08 (2006.01) C07D 471/18 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2446795

Diazabicyclo[3.3.1]nonane derivatives that inhibit the peptidyl-prolyl isomerase enzyme activity associated with FK-506 binding proteins (FKBP) are described for treating neurological disorders. Also described are compounds useful for preparing such inhibitors.

L'invention concerne des dérivés de diazabicyclo[3.3.1]nonane qui inhibent l'activité enzymatique peptidyl-prolyl isomérase associée aux protéines de fixation de FK-506, pour le traitement des troubles neurologiques. L'invention concerne également des composés utiles dans l'élaboration de ce type d'inhibiteur.

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