C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/361.1, 260/3
C07D 307/85 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 1333603
Highly effective diuretic antihypertensives, i.e., sulfamoyl-2-benzofurancarboxylic acid derivatives which are classified as loop diuretics with less adverse side-effects and which can be administered orally, have the formula Image wherein R is hydrogen or a protecting group; R1 and R2 are the same or different and each is hydrogen, lower alkyl, 4- to 7-membered cycloalkyl, optionally substituted phenyl, phenyl-lower alkyl, lower alkoxy- carbonyl, or morpholino-lower alkyl, or R1 and R2 taken together with the adjacent nitrogen atom may form an optionally substituted 5- or 6-membered heterocycle which may have an additional one or more hetero atoms; and X and X' are each independently hydrogen or halogen.
577580
Harada Hiroshi
Matsushita Yoshihiro
Nakamura Masuhisa
Yonetani Yukio
Johnson Douglas S. Q.c.
Shionogi & Co. Ltd.
LandOfFree
Sulfamoyl-2-benzofurancarboxylic acid derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sulfamoyl-2-benzofurancarboxylic acid derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sulfamoyl-2-benzofurancarboxylic acid derivative will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1174748