Sulfamoyl sulfonate prodrugs

C - Chemistry – Metallurgy – 07 – J

Patent

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Details

C07J 41/00 (2006.01) A61K 31/565 (2006.01) A61P 5/26 (2006.01) A61P 5/30 (2006.01)

Patent

CA 2632272

The invention relates to the sulfamoyl sulfonate prodrugs of general formula (I), to a method for producing them, to pharmaceutical compositions containing the same and to their use for producing orally available drugs. The compounds according to the invention bind to carboanhydrases and inhibit these enzymes.

La présente invention concerne des promédicaments de sulfonate de sulfamoyle de formule générale (I), un procédé pour produire ceux-ci, des compositions pharmaceutiques contenant ces composés, ainsi que leur utilisation pour produire des médicaments qui peuvent être administrés par voie orale. Les composés selon cette invention se lient à des carboanhydrases et inhibent ces enzymes.

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