Sulfanyl derivatives and their use as synthesis intermediates

Details Sulfanyl derivatives and their use as synthesis intermediates Sulfanyl derivatives and their use as synthesis intermediates

C - Chemistry, Metallurgy

07

C

C07C 329/16 (2006.01) C07C 333/26 (2006.01)

Patent

CA 2695075

The present application relates to sulfanyl derivatives of formula (I) and to their use as synthesis intermediates, especially for the preparation of the pharmaceutically active compound mesna. Formula (I), wherein X is O or N-C(NH)NH2; M + is hydrogen, sodium, disodium, potassium, dipotassium, ammonium (NH4)+, diammonium, quaternary ammonium, calcium or magnesium.

Cette invention a trait à des dérivés du sulfanyle de formule (I) et à leur utilisation en tant qu'intermédiaires de synthèse, en particulier dans la préparation du mesna, composé pharmaceutiquement actif. Dans la formule (I), X est O ou N-C(NH)NH2 ; M + est hydrogène, sodium, un composé disodique, potassium, un composé dipotassique, ammonium (NH4)+, un composé diammonique, un ammonium quaternaire, calcium ou magnésium.

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