Sulfate of quinolonecarboxylic acid derivatives and the use...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/04 (2006.01) C07D 215/56 (2006.01)

Patent

CA 2399516

The invention provides a novel sulfate salt and a hydrate thereof, which are useful in efficient recovery of 1-cyclopropyl-7-(3-methyl-1-piperazinyl)-6- fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid. Specifically, the invention provides a sulfate salt of 1-cyclopropyl-7-(3-methyl-1- piperazinyl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and a hydrate of the salt, and industrial use of both.

Cette invention concerne un nouveau sel de sulfate et un hydrate de ce sel qui sont utiles pour la récupération d'acide 1-cyclopropyl-7-(3-méthyl-1-pipérazinyl)-6-fluoro-8-méthoxy-1,4-dihydro-4-oxo-3-quinoléine carboxylique. Plus précisément, l'invention porte sur un sel de sulfate d'acide 1-cyclopropyl-7-(3-méthyl-1-pipérazinyl)-6-fluoro-8-méthoxy-1,4-dihydro-4-oxo-3-quinoléine carboxylique et un hydrate de ce sel, ainsi que sur l'utilisation industrielle de ces deux composés.

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