Sulfated glycosaminoglycanoid derivatives

Details Sulfated glycosaminoglycanoid derivatives Sulfated glycosaminoglycanoid derivatives

C - Chemistry, Metallurgy

07

H

C07H 15/04 (2006.01) A61K 31/70 (2006.01) A61K 31/715 (2006.01) A61P 7/02 (2006.01) A61P 35/00 (2006.01) C07H 5/08 (2006.01) C07H 11/00 (2006.01) C07H 15/00 (2006.01) C07H 15/08 (2006.01) C07H 15/18 (2006.01) C07H 15/20 (2006.01) C07H 15/203 (2006.01) C07H 15/26 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2076063

The invention relates to a sulfated glycosaminoglycanoid derivative or a pharmaceutically acceptable salt thereof, of which the functional N-sulfate, N-acetate, and hydroxy groups, are replaced by alkoxy, aryloxy, aralkoxy, O-sulfate, or OALK(OALK)n OX groups (wherein ALK is an aliphatic hydrocarbon group, n is 0-5, and X is an alkyl or aryl group), provided that at least two functional groups are not replaced by O-sulfate. The compounds have antithrombotic and smooth muscle cell proliferation inhibiting activities.

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