Sulfated polysaccharides and uses thereof in medical treatment

Details Sulfated polysaccharides and uses thereof in medical treatment Sulfated polysaccharides and uses thereof in medical treatment

A - Human Necessities

61

L

A61L 15/28 (2006.01) A61K 9/70 (2006.01) A61K 31/715 (2006.01) A61K 31/717 (2006.01) A61K 31/737 (2006.01) A61P 17/02 (2006.01) C08B 15/00 (2006.01) C08B 37/04 (2006.01)

Patent

CA 2265780

The invention provides sulfated oxidised regenerated cellulose compounds, sulfated alginates, and the salts and hydrates thereof. The compounds are obtained by sulfation of oxidised regenerated cellulose with sulfur trioxide. The invention also provides pharmaceutical compositions comprising the compounds, in particular compositions for the treatment of medical conditions mediated by a matrix metalloproteinase and anticoagulant pharmaceutical compositions.

La présente invention concerne des composés de cellulose régénérée sulfatée oxydée, des alginates sulfatés, et les sels et hydrates de ces derniers. Ces composés sont obtenus par sulfatation de cellulose régénérée oxydée avec du trioxyde de soufre. L'invention se rapporte également à des compositions pharmaceutiques comprenant lesdits composés, en particulier des compositions destinées au traitement d'états pathologiques induits par une métalloprotéinase matricielle et des compositions pharmaceutiques anticoagulantes.

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