C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/10 (2006.01) C07H 3/06 (2006.01) C07H 17/04 (2006.01) C08B 37/00 (2006.01) A61K 31/725 (1990.01)
Patent
CA 2108569
2108569 9218546 PCTABS00016 Highly sulfated oligosaccharides in the form of hexasaccharide and octasaccharide compounds which have antiproliferative activity with respect to smooth muscle cells are useful in treatment of conditions characterized by unwanted smooth muscle cell proliferation such as a result of trauma or disease states such as asthma, congestive heart failure and hypertension. The oligosaccharides have increased ability to inhibit the proliferation of smooth muscle cells and decreased ability to act as an anticoagulant as compared with commercial heparin and/or unseparated fragments of heparin.
Brandley Brian K.
Conrad H. Edward
Fugedi Peter
Laine Roger A.
Lam Lun H.
Brandley Brian K.
Conrad H. Edward
Fetherstonhaugh & Co.
Fugedi Peter
Glycomed Incorporated
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