Sulfonamide compounds and uses thereof as medicines

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/08 (2006.01) A61P 11/08 (2006.01) A61P 37/08 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2352871

Sulfonamide compounds represented by general formula (I), or salts thereof; and drug compositions containing the same (wherein each symbol is as defined in the description). These compounds serve as preventive or therapeutic agents efficacious against diseases which can be cured through decrease in blood sugar level and those which can be cured through inhibition of cGMP-PDE, relaxation of smooth muscle, bronchodilation, vasodilation, inhibition of smooth muscle fiber, or inhibition of allergy.

L'invention porte sur des composés de sulfamide représentés par la formule (I) ou leurs sels ; et des compositions de médicaments contenant ces mêmes composés. Ces composés sont utilisés en tant qu'agents prophylactiques ou thérapeutiques efficaces contre des maladies qui peuvent être soignées au moyen de la diminution de la glycémie et les maladies qui peuvent être soignées via l'inhibition de cGMP-PDE, le relâchement des muscles lisses, la bronchodilatation, la vasodilatation, l'inhibition des fibres des muscles lisses ou l'inhibition de l'allergie. Formule (I) (dans laquelle chaque symbole est tel que défini dans le descriptif).

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