Sulfonamide compounds for the treatment of respiratory...

Details Sulfonamide compounds for the treatment of respiratory... Sulfonamide compounds for the treatment of respiratory...

C - Chemistry, Metallurgy

07

D

C07D 231/18 (2006.01) A61K 31/415 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2748331

Compounds of formula (I) are agonists of PPAR.gamma., useful for the treatment of respiratory disease; formula (I): wherein R1, R2 or R3 each independently represents halo, cyano, nitro, amino, alkyl, haloalkyl, alkoxy, haloalkoxy, carboxylic acid or an ester or amide thereof; R4 represents hydrogen or alkyl; m, n or p independently represents 0, 1, 2 or 3.

La présente invention concerne des composés de formule (I) qui sont des agonistes de PPAR?, utiles pour le traitement de maladies respiratoires; (formule (I)). R1, R2 ou R3 représentent chacun indépendamment un halogéno, un cyano, un nitro, un amino, un alkyle, un halogénoalkyle, un alcoxy, un halogénoalcoxy, un acide carboxylique ou un ester ou un amide de celui-ci; R4 représente un hydrogène ou un alkyle; m, n ou p représentent indépendamment 0, 1, 2 ou 3.

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