Sulfonamide derivatives

Details Sulfonamide derivatives Sulfonamide derivatives

C - Chemistry, Metallurgy

07

D

C07D 207/48 (2006.01) A61K 31/395 (2006.01) C07C 311/29 (2006.01) C07C 311/64 (2006.01) C07D 203/24 (2006.01) C07D 209/04 (2006.01) C07D 209/42 (2006.01) C07D 211/58 (2006.01) C07D 211/96 (2006.01) C07D 213/42 (2006.01) C07D 233/56 (2006.01) C07D 235/02 (2006.01) C07D 235/22 (2006.01) C07D 239/42 (2006.01) C07D 241/04 (2006.01) C07D 257/04 (2006.01) C07D 263/26 (2006.01) C07D 263/38 (2006.01) C07D 265/36 (2006.01) C07D 277/06 (2006.01) C07D 277/56 (2006.01) C07D 295/155 (2006.01) C07D 295/26 (2006.01) C07D

Patent

CA 2186665

Sulfonamide derivatives of the formula (I) Image (I) wherein R1 is, inter alia, alkyl, alkoxy, hydroxy, keto, nitro, halogen, trihalomethyl, cyano, amidino and -COOR7 (in which R7 is hydrogen or alkyl), n is an integer from 0 to 5; Image is a carbocyclic ring or heterocyclic ring; Image is Image in which R2 and R3 each is hydrogen, alkyl, alkoxy, halogen, trihalomethyl or phenyl, or R2 and R3, taken together, represent alkylidene, or Image is Image in which R2 and R3, taken together with the carbon atom to which they are attached represent cycloalkyl; R4 is alkyl or alkoxy or two of R4, attached to the benzene nucleus at ortho positions relative to each other, taken together, represent alkylene; m is an integer from 0 to 4; and Image is optionally substituted amino or a nitrogen-containing ring, are described as new pharmaceutical compounds having inhibitory activity or elastase.

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