Sulfonamide derivatives as chymase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/42 (2006.01) A61K 31/4436 (2006.01) A61P 11/00 (2006.01) C07D 333/62 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2674644

The invention is concerned with novel sulfonamide derivatives of formula (I) wherein A, R1 to R2'', X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit chymase and can be used as medicaments.

La présente invention concerne des dérivés innovants de sulfonamide de formule (I), dans laquelle A, R1 à R2'', X et Y sont tels que définis dans la description et les revendications, de même que leurs sels physiologiquement acceptables. Ces composés inhibent la chymase et ils peuvent être utilisés en tant que médicaments.

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